Sag (NM_009118) Mouse Recombinant Protein
Product Specifications
Background
Binds to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO (PubMed:9333241, PubMed:16421323) . May play a role in preventing light-dependent degeneration of retinal photoreceptor cells (PubMed:16421323) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse S-antigen, retina and pineal gland (arrestin) (Sag), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
A930001K18Rik; Arr1; arrestin; Irbp
Gene ID
20215
UniProt
P20443, Q3UPX6
Accession Number mRNA
NM_009118
Chromosomal Location
1 44.44 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
44.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Sag
Species
Mouse
Protein ID
NP_033144
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/20215
Uniprot URL
https://www.uniprot.org/uniprot/P20443
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009118
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_033144
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