Pten (NM_008960) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes a phosphatase with dual activity against phospholipids and proteins, and acts as a tumor-suppressor. The protein contains four structural domains, a PIP2-binding domain, a catalytic tensin-type phosphatase domain, a C2 tensin-type domain and a PDZ-binding domain. The protein belongs to the protein tyrosine phosphatase family. Deletion of this gene in mice contribute to tumorigenesis in multiple tissues. [provided by RefSeq, Sep 2015]
Overview
Purified recombinant protein of Mouse phosphatase and tensin homolog (Pten), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; MMAC; MMAC1; PTENbeta; TEP; TEP1
Gene ID
19211
UniProt
O08586, Q3UUT8
Accession Number mRNA
NM_008960
Chromosomal Location
19 28.14 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
47.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Pten
Species
Mouse
Protein ID
NP_032986
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19211
Uniprot URL
https://www.uniprot.org/uniprot/O08586
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_008960
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_032986
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