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Pten (NM_008960) Mouse Recombinant Protein

Product Specifications

Background

This gene encodes a phosphatase with dual activity against phospholipids and proteins, and acts as a tumor-suppressor. The protein contains four structural domains, a PIP2-binding domain, a catalytic tensin-type phosphatase domain, a C2 tensin-type domain and a PDZ-binding domain. The protein belongs to the protein tyrosine phosphatase family. Deletion of this gene in mice contribute to tumorigenesis in multiple tissues. [provided by RefSeq, Sep 2015]

Overview

Purified recombinant protein of Mouse phosphatase and tensin homolog (Pten), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; MMAC; MMAC1; PTENbeta; TEP; TEP1

Gene ID

19211

UniProt

O08586, Q3UUT8

Accession Number mRNA

NM_008960

Chromosomal Location

19 28.14 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

47.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Pten

Species

Mouse

Protein ID

NP_032986

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/19211

Uniprot URL

https://www.uniprot.org/uniprot/O08586

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_008960

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_032986

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