Malabaricone B

Malabaricone B, a naturally occurring plant phenolic, is an orally active α-glucosidase inhibitor with an IC50 of 63.7 μM. Malabaricone B has anticancer, antimicrobial, anti-oxidation and antidiabetic activities[1][2][3].

Product Specifications

CAS Number

[63335-24-0]

UNSPSC

12352005

Target

Apoptosis; Glycosidase

Type

Natural Products

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/malabaricone-b.html

Purity

99.58

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=C(O)C=CC=C1O)CCCCCCCCC2=CC=C(O)C=C2

Molecular Formula

C21H26O4

Molecular Weight

342.43

References & Citations

[1]Mrityunjay Tyagi, et al. Spice-derived phenolic, malabaricone B induces mitochondrial damage in lung cancer cells via a p53-independent pathway. Food Funct. 2018 Nov 14;9 (11) :5715-5727.|[2]K Y Orabi, et al. Isolation and characterization of two antimicrobial agents from mace (Myristica fragrans) . J Nat Prod. May-Jun 1991;54 (3) :856-9. |[3]B Prabha, et al. Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair. Bioorg Med Chem. 2018 Jul 23;26 (12) :3461-3467.