Traf1 (NM_009421) Mouse Recombinant Protein
Selected Variant
PM46595M5
Size: 20 µg
Product Specifications
Background
Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2 (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse TNF receptor-associated factor 1 (Traf1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
4732496E14Rik
Gene ID
22029
UniProt
P39428
Accession Number mRNA
NM_009421
Chromosomal Location
2 B
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
45.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Traf1
Species
Mouse
Protein ID
NP_033447
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/22029
Uniprot URL
https://www.uniprot.org/uniprot/P39428
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009421
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_033447
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