Dok2 (NM_010071) Mouse Recombinant Protein
Product Specifications
Background
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation.[UniProtKB/Swiss-Prot Function]
Synonyms
Dok-R; DokR; Frip
Gene ID
13449
UniProt
O70469, Q3TX09
Accession Number mRNA
NM_010071
Chromosomal Location
14 36.71 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
45.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Dok2
Species
Mouse
Protein ID
NP_034201
Overview
Purified recombinant protein of Mouse docking protein 2 (Dok2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/13449
Uniprot URL
https://www.uniprot.org/uniprot/O70469
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010071
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034201
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