Dok2 (NM_010071) Mouse Recombinant Protein

Product Specifications

Background

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse docking protein 2 (Dok2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Dok-R; DokR; Frip

Gene ID

13449

UniProt

O70469, Q3TX09

Accession Number mRNA

NM_010071

Chromosomal Location

14 36.71 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

45.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.