Wwox (NM_019573) Mouse Recombinant Protein

Product Specifications

Background

Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm (By similarity) . May also play a role in tumor necrosis factor (TNF) -mediated cell death. Required for normal bone development.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse WW domain-containing oxidoreductase (Wwox), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

5330426P09Rik; 9030416C10Rik; WOX1

Gene ID

80707

UniProt

Q91WL8

Accession Number mRNA

NM_019573

Chromosomal Location

8 E1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

46.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.