Wwox (NM_019573) Mouse Recombinant Protein
Product Specifications
Background
Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm (By similarity) . May also play a role in tumor necrosis factor (TNF) -mediated cell death. Required for normal bone development.[UniProtKB/Swiss-Prot Function]
Synonyms
5330426P09Rik; 9030416C10Rik; WOX1
Gene ID
80707
UniProt
Q91WL8
Accession Number mRNA
NM_019573
Chromosomal Location
8 E1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
46.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Wwox
Species
Mouse
Protein ID
NP_062519
Overview
Purified recombinant protein of Mouse WW domain-containing oxidoreductase (Wwox), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/80707
Uniprot URL
https://www.uniprot.org/uniprot/Q91WL8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_019573
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_062519
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