Klf15 (NM_023184) Mouse Recombinant Protein
Product Specifications
Background
Transcriptional regulator that binds to the GA element of the CLCNKA promoter (By similarity) . Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart. Is a repressor of CCN2 expression, involved in the control of cardiac fibrosis. Is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A, GATA4 and MYOCD activity. Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation (By similarity) . Involved in podocyte differentiation.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse Kruppel-like factor 15 (Klf15), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1810013I09Rik; AV048136; AW494632; CKLF; KKLF
Gene ID
66277
UniProt
Q9EPW2
Accession Number mRNA
NM_023184
Chromosomal Location
6 D1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
44.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Klf15
Species
Mouse
Protein ID
NP_075673
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66277
Uniprot URL
https://www.uniprot.org/uniprot/Q9EPW2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_023184
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_075673
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