Casq2 (NM_009814) Mouse Recombinant Protein
Product Specifications
Background
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca (2+) ions. Regulates the release of lumenal Ca (2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.[UniProtKB/Swiss-Prot Function]
Synonyms
AA033488; AW146219; cCSQ; Csq2; ESTM52
Gene ID
12373
UniProt
O09161
Accession Number mRNA
NM_009814
Chromosomal Location
3 F2.2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
48.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Casq2
Species
Mouse
Protein ID
NP_033944
Overview
Purified recombinant protein of Mouse calsequestrin 2 (Casq2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12373
Uniprot URL
https://www.uniprot.org/uniprot/O09161
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009814
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_033944
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