Pdk3 (NM_145630) Mouse Recombinant Protein
Selected Variant
PM46547M5
Size: 20 µg
Product Specifications
Background
Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse pyruvate dehydrogenase kinase, isoenzyme 3 (Pdk3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2610001M10Rik; AI035637
Gene ID
236900
UniProt
Q922H2, Q4FJR4
Accession Number mRNA
NM_145630
Chromosomal Location
X C3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
47.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Pdk3
Species
Mouse
Protein ID
NP_663605
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/236900
Uniprot URL
https://www.uniprot.org/uniprot/Q922H2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_145630
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_663605
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