Calr (NM_007591) Mouse Recombinant Protein
Product Specifications
Background
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
Calregulin; CRT
Gene ID
12317
UniProt
P14211, B2MWM9
Accession Number mRNA
NM_007591
Chromosomal Location
8 41.21 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
48 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Calr
Species
Mouse
Protein ID
NP_031617
Overview
Purified recombinant protein of Mouse calreticulin (Calr), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12317
Uniprot URL
https://www.uniprot.org/uniprot/P14211
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007591
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031617
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