Rnf135 (NM_028019) Mouse Recombinant Protein
Selected Variant
PM46529M5
Size: 20 µg
Product Specifications
Background
Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse ring finger protein 135 (Rnf135), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
0610037N03Rik; 2410006N06Rik
Gene ID
71956
UniProt
Q9CWS1, B2RRA5
Accession Number mRNA
NM_028019
Chromosomal Location
11 47.59 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
46.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Rnf135
Species
Mouse
Protein ID
NP_082295
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/71956
Uniprot URL
https://www.uniprot.org/uniprot/Q9CWS1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_028019
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_082295
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