Brf2 (NM_025686) Mouse Recombinant Protein
Product Specifications
Background
General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress.[UniProtKB/Swiss-Prot Function]
Synonyms
2700059M06Rik; 5730512K07Rik; AU018504; AU022602; BRFU; TFIIIB50
Gene ID
66653
UniProt
Q3UAW9, A0A0R4J0C6
Accession Number mRNA
NM_025686
Chromosomal Location
8 A2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
47.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Brf2
Species
Mouse
Protein ID
NP_079962
Overview
Purified recombinant protein of Mouse BRF2, RNA polymerase III transcription initiation factor 50kDa subunit (Brf2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66653
Uniprot URL
https://www.uniprot.org/uniprot/Q3UAW9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025686
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079962
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