Dnmt3l (NM_019448) Mouse Recombinant Protein

Product Specifications

Background

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein that is a catalytically inactive regulatory factor of DNA methyltransferases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

Overview

Purified recombinant protein of Mouse DNA (cytosine-5-) -methyltransferase 3-like (Dnmt3l), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

D6Ertd14; D6Ertd14e; ecat; ecat7

Gene ID

54427

UniProt

Q9CWR8, A3EWM2

Accession Number mRNA

NM_019448

Chromosomal Location

10 39.72 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

48 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.