Terf1 (NM_009352) Mouse Recombinant Protein

Product Specifications

Background

This gene encodes a protein that binds to repeats in telomeres to form a nucleoprotein complex that protects against the degradation of chromosomal ends. The encoded protein regulates the length of telomeres and is an integral structural component of the functional telomere. This protein is thought to play a role in spindle formation in mitosis. Mutations in this gene are associated with bone marrow failure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2013]

Overview

Purified recombinant protein of Mouse telomeric repeat binding factor 1 (Terf1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

P; Pin2; Trbf; Trbf1; Trf; Trf1

Gene ID

21749

UniProt

P70371

Accession Number mRNA

NM_009352

Chromosomal Location

1 4.88 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

48.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.