Ppard (NM_011145) Mouse Recombinant Protein
Product Specifications
Background
Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse peroxisome proliferator activator receptor delta (Ppard), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Nr1c2; NUC-1; NUC1; PPAR-beta; PPAR-delta; Pparb; Pparb/d; PPARdelta; PPAR[b]
Gene ID
19015
UniProt
P35396, Q546I3
Accession Number mRNA
NM_011145
Chromosomal Location
17 14.64 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
50.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ppard
Species
Mouse
Protein ID
NP_035275
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19015
Uniprot URL
https://www.uniprot.org/uniprot/P35396
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_011145
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_035275
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