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Ppard (NM_011145) Mouse Recombinant Protein

Product Specifications

Background

Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse peroxisome proliferator activator receptor delta (Ppard), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Nr1c2; NUC-1; NUC1; PPAR-beta; PPAR-delta; Pparb; Pparb/d; PPARdelta; PPAR[b]

Gene ID

19015

UniProt

P35396, Q546I3

Accession Number mRNA

NM_011145

Chromosomal Location

17 14.64 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

50.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Ppard

Species

Mouse

Protein ID

NP_035275

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/19015

Uniprot URL

https://www.uniprot.org/uniprot/P35396

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_011145

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_035275

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