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Ubxn6 (NM_024432) Mouse Recombinant Protein

Product Specifications

Background

May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes. As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation. It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse UBX domain protein 6 (Ubxn6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1200008L11Rik; 2210415J11Rik; AU040909; Ubxd1; Ubxdc2

Gene ID

66530

UniProt

Q99PL6

Accession Number mRNA

NM_024432

Chromosomal Location

17 D

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

49.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Ubxn6

Species

Mouse

Protein ID

NP_077752

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/66530

Uniprot URL

https://www.uniprot.org/uniprot/Q99PL6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_024432

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_077752

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