Faf2 (NM_178397) Mouse Recombinant Protein

Product Specifications

Background

Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway. Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse Fas associated factor family member 2 (Faf2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

2210404D11Rik; AI462440; mKIAA0887; Ubxd8

Gene ID

76577

UniProt

Q3TDN2

Accession Number mRNA

NM_178397

Chromosomal Location

13 B1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

52.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.