Pdia6 (NM_027959) Mouse Recombinant Protein
Product Specifications
Background
May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:24508390) . Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (By similarity) . May also regulate the UPR via the EIF2AK3 UPR sensor (By similarity) . Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse protein disulfide isomerase associated 6 (Pdia6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1700015E05Rik; AL023058; C77895; CaBP5; P5; Txndc7
Gene ID
71853
UniProt
Q922R8, Q3TML0
Accession Number mRNA
NM_027959
Chromosomal Location
12 A1.1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
48.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Pdia6
Species
Mouse
Protein ID
NP_082235
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/71853
Uniprot URL
https://www.uniprot.org/uniprot/Q922R8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_027959
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_082235
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