Pdia6 (NM_027959) Mouse Recombinant Protein

Product Specifications

Background

May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:24508390) . Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (By similarity) . May also regulate the UPR via the EIF2AK3 UPR sensor (By similarity) . Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse protein disulfide isomerase associated 6 (Pdia6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1700015E05Rik; AL023058; C77895; CaBP5; P5; Txndc7

Gene ID

71853

UniProt

Q922R8, Q3TML0

Accession Number mRNA

NM_027959

Chromosomal Location

12 A1.1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

48.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.