F7 (NM_010172) Mouse Recombinant Protein
Selected Variant
PM46328M5
Size: 20 µg
Product Specifications
Background
This gene encodes a vitamin K-dependent serine protease that plays a critical role in the extrinsic pathway of blood coagulation. Upon contact with tissue factor III (TF III), the encoded protein forms an activated complex termed TF-FVIIa that initiates the coagulation cascade involving other coagulation factors, ultimately resulting in a fibrin clot. Complete lack of the encoded protein in mice results in in perinatal lethality due to bleeding from normal blood vessels. [provided by RefSeq, Apr 2015]
Overview
Purified recombinant protein of Mouse coagulation factor VII (F7), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AI132620; Cf7; F; FVII
Gene ID
14068
UniProt
P70375, Q542C2
Accession Number mRNA
NM_010172
Chromosomal Location
8 5.73 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
50.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
F7
Species
Mouse
Protein ID
NP_034302
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/14068
Uniprot URL
https://www.uniprot.org/uniprot/P70375
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010172
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034302
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