Arhgap15 (BC034881) Mouse Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a RAC GTPase-activating protein that is regulated through its PH domain and by recruitment to the membrane. The protein accelerates hydrolysis of guanosine triphosphate to guanosine diphosphate to repress Rac activity. Knock-out of Arhgap15 function demonstrates that this gene is required to regulate multiple functions in macrophages and neutrophils. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]
Overview
Purified recombinant protein of Mouse Rho GTPase activating protein 15 (cDNA clone MGC:41314 IMAGE:3468639), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
5830480G12Rik
Gene ID
76117
UniProt
Q811M1
Accession Number mRNA
BC034881
Chromosomal Location
2 B
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
51.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Arhgap15
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/76117
Uniprot URL
https://www.uniprot.org/uniprot/Q811M1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC034881
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