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Arhgap15 (BC034881) Mouse Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a RAC GTPase-activating protein that is regulated through its PH domain and by recruitment to the membrane. The protein accelerates hydrolysis of guanosine triphosphate to guanosine diphosphate to repress Rac activity. Knock-out of Arhgap15 function demonstrates that this gene is required to regulate multiple functions in macrophages and neutrophils. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]

Overview

Purified recombinant protein of Mouse Rho GTPase activating protein 15 (cDNA clone MGC:41314 IMAGE:3468639), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

5830480G12Rik

Gene ID

76117

UniProt

Q811M1

Accession Number mRNA

BC034881

Chromosomal Location

2 B

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

51.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Arhgap15

Species

Mouse

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/76117

Uniprot URL

https://www.uniprot.org/uniprot/Q811M1

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/BC034881

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