Tubb3 (NM_023279) Mouse Recombinant Protein
Product Specifications
Background
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance. Binding of NTN1/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (PubMed:28483977) . Plays a role in dorsal root ganglion axon projection towards the spinal cord (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
3200002H15Rik; M (beta) 3; M (beta) 6
Gene ID
22152
UniProt
Q9ERD7
Accession Number mRNA
NM_023279
Chromosomal Location
8 E1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
50.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Tubb3
Species
Mouse
Protein ID
NP_075768
Overview
Purified recombinant protein of Mouse tubulin, beta 3 class III (Tubb3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/22152
Uniprot URL
https://www.uniprot.org/uniprot/Q9ERD7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_023279
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_075768
Curated Selection
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