Ilk (NM_010562) Mouse Recombinant Protein
Product Specifications
Background
Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.[UniProtKB/Swiss-Prot Function]
Synonyms
AA511515; ESTM24
Gene ID
16202
UniProt
O55222
Accession Number mRNA
NM_010562
Chromosomal Location
7 E3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
51.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ilk
Species
Mouse
Protein ID
NP_034692
Overview
Purified recombinant protein of Mouse integrin linked kinase (Ilk), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/16202
Uniprot URL
https://www.uniprot.org/uniprot/O55222
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010562
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034692
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