Ccm2 (NM_146014) Mouse Recombinant Protein
Product Specifications
Background
Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions. May also function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse cerebral cavernous malformation 2 (Ccm2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
BC029157
Gene ID
216527
UniProt
Q8K2Y9
Accession Number mRNA
NM_146014
Chromosomal Location
11 A1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
49.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ccm2
Species
Mouse
Protein ID
NP_666126
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/216527
Uniprot URL
https://www.uniprot.org/uniprot/Q8K2Y9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_146014
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_666126
Curated Selection
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