Casp9 (NM_015733) Mouse Recombinant Protein
Product Specifications
Background
This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, the initiator caspase, is activated after cytochrome c release from mitochondria and targets downstream effectors. In mouse, deficiency of this gene can cause perinatal lethality. This protein may have a role in normal brain development. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013]
Overview
Purified recombinant protein of Mouse caspase 9 (Casp9), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AI115399; APAF-3; AW493809; Casp; CASP-9; Caspase-9; ICE-; ICE-LAP6; Mch6
Gene ID
12371
UniProt
Q8C3Q9
Accession Number mRNA
NM_015733
Chromosomal Location
4 D3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
50 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Casp9
Species
Mouse
Protein ID
NP_056548
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12371
Uniprot URL
https://www.uniprot.org/uniprot/Q8C3Q9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015733
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_056548
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