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Dlst (NM_030225) Mouse Recombinant Protein

Product Specifications

Background

Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex (By similarity) . The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO (2) (By similarity) . The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Dlst), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1600017E01Rik; 4632413C10Rik; 4930529O08Rik; DLTS

Gene ID

78920

UniProt

Q9D2G2

Accession Number mRNA

NM_030225

Chromosomal Location

12 D1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

49.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Dlst

Species

Mouse

Protein ID

NP_084501

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/78920

Uniprot URL

https://www.uniprot.org/uniprot/Q9D2G2

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_030225

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_084501

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