C80913 (BC023029) Mouse Recombinant Protein
Product Specifications
Background
Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
Rmp, NNX3
Gene ID
19777
UniProt
Q3TLD5
Accession Number mRNA
BC023029
Chromosomal Location
7 B3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
50.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
C80913
Species
Mouse
Overview
Purified recombinant protein of Mouse expressed sequence C80913 (cDNA clone MGC:36045 IMAGE:5374731), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19777
Uniprot URL
https://www.uniprot.org/uniprot/Q3TLD5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC023029
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