Sh3bp5 (NM_011894) Mouse Recombinant Protein
Selected Variant
PM46252M5
Size: 20 µg
Product Specifications
Background
Functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25 (By similarity) . Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse SH3-domain binding protein 5 (BTK-associated) (Sh3bp5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AI606498; Sab; SH3BP-5
Gene ID
24056
UniProt
Q9Z131
Accession Number mRNA
NM_011894
Chromosomal Location
14 B
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
51.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Sh3bp5
Species
Mouse
Protein ID
NP_036024
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/24056
Uniprot URL
https://www.uniprot.org/uniprot/Q9Z131
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_011894
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036024
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