Riox2 (NM_025910) Mouse Recombinant Protein
Product Specifications
Background
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39' (By similarity) . May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse ribosomal oxygenase 2 (Riox2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1810047J07Rik; 2410057H13Rik; 3830408E23Rik; AI449204
Gene ID
67014
UniProt
Q8CD15
Accession Number mRNA
NM_025910
Chromosomal Location
16 C1.3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
53.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Riox2
Species
Mouse
Protein ID
NP_080186
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/67014
Uniprot URL
https://www.uniprot.org/uniprot/Q8CD15
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025910
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_080186
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