Nectin2 (NM_001159724) Mouse Recombinant Protein

Product Specifications

Background

Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse nectin cell adhesion molecule 2 (Nectin2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AI325026; AI987993; Cd112; MPH; nectin-2; Pvr; Pvrl2; Pvs

Gene ID

19294

UniProt

P32507, Q8C6F2

Accession Number mRNA

NM_001159724

Chromosomal Location

7 9.94 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

50.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.