Nectin2 (NM_001159724) Mouse Recombinant Protein
Product Specifications
Background
Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse nectin cell adhesion molecule 2 (Nectin2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AI325026; AI987993; Cd112; MPH; nectin-2; Pvr; Pvrl2; Pvs
Gene ID
19294
UniProt
P32507, Q8C6F2
Accession Number mRNA
NM_001159724
Chromosomal Location
7 9.94 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
50.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Nectin2
Species
Mouse
Protein ID
NP_001153196
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19294
Uniprot URL
https://www.uniprot.org/uniprot/P32507
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001159724
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001153196
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