Ryk (BC032275) Mouse Recombinant Protein
Product Specifications
Background
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse receptor-like tyrosine kinase (cDNA clone MGC:40871 IMAGE:5370100), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Vik, ERK-3
Gene ID
20187
UniProt
Q01887
Accession Number mRNA
BC032275
Chromosomal Location
9 54.72 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
73.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ryk
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/20187
Uniprot URL
https://www.uniprot.org/uniprot/Q01887
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC032275
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