Camk2a (NM_177407) Mouse Recombinant Protein
Product Specifications
Background
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca (2+) /calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity) . Regulates dendritic spine development. Also regulates the migration of developing neurons (By similarity) . Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity (PubMed:23805378) .[UniProtKB/Swiss-Prot Function]
Synonyms
CaMKII; mKIAA0968; R74975
Gene ID
12322
UniProt
P11798
Accession Number mRNA
NM_177407
Chromosomal Location
18 34.41 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
54.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Camk2a
Species
Mouse
Protein ID
NP_803126
Overview
Purified recombinant protein of Mouse calcium/calmodulin-dependent protein kinase II alpha (Camk2a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12322
Uniprot URL
https://www.uniprot.org/uniprot/P11798
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_177407
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_803126
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