Dok1 (NM_010070) Mouse Recombinant Protein
Selected Variant
PM46100M5
Size: 20 µg
Product Specifications
Background
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3 (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse docking protein 1 (Dok1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AW557123; p62DOK
Gene ID
13448
UniProt
P97465, Q3UWF9
Accession Number mRNA
NM_010070
Chromosomal Location
6 35.94 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
52.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Dok1
Species
Mouse
Protein ID
NP_034200
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/13448
Uniprot URL
https://www.uniprot.org/uniprot/P97465
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010070
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034200
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