Fscn1 (NM_007984) Mouse Recombinant Protein

Product Specifications

Background

Actin-binding protein that contains 2 major actin binding sites (By similarity) . Organizes filamentous actin into parallel bundles (PubMed:7738015) . Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers (By similarity) . Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration (PubMed:21685497) . Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse fascin actin-bundling protein 1 (Fscn1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AI663989; Fan1; fascin-1

Gene ID

14086

UniProt

Q61553

Accession Number mRNA

NM_007984

Chromosomal Location

5 81.84 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

55 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.