Trmt6 (NM_175113) Mouse Recombinant Protein

Product Specifications

Background

Substrate-binding subunit of tRNA (adenine-N (1) -) -methyltransferase, which catalyzes the formation of N (1) -methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Together with the TRMT61A catalytic subunit, part of a mRNA N (1) -methyltransferase complex that mediates methylation of adenosine residues at the N (1) position of a small subset of mRNAs: N (1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse tRNA methyltransferase 6 (Trmt6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

3300001M20Rik; AU016412; AW492787; CGI-09; mKIAA1153

Gene ID

66926

UniProt

Q8CE96

Accession Number mRNA

NM_175113

Chromosomal Location

2 F2

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

55.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.