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Ppp2r5b (NM_198168) Mouse Recombinant Protein

Product Specifications

Background

As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse protein phosphatase 2, regulatory subunit B', beta (Ppp2r5b), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

B'beta; BC026670

Gene ID

225849

UniProt

Q6PD28

Accession Number mRNA

NM_198168

Chromosomal Location

19 A

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

57.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Ppp2r5b

Species

Mouse

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/225849

Uniprot URL

https://www.uniprot.org/uniprot/Q6PD28

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_198168

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