Acvrl1 (NM_009612) Mouse Recombinant Protein
Product Specifications
Background
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse activin A receptor, type II-like 1 (Acvrl1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Acvrlk1; AI115505; AI427544; Alk1
Gene ID
11482
UniProt
Q61288
Accession Number mRNA
NM_009612
Chromosomal Location
15 F1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
56.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Acvrl1
Species
Mouse
Protein ID
NP_033742
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11482
Uniprot URL
https://www.uniprot.org/uniprot/Q61288
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009612
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_033742
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