Cyp7b1 (NM_007825) Mouse Recombinant Protein
Product Specifications
Background
Oxysterol 7alpha-hydroxylase that mediates formation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) from 25-hydroxycholesterol (PubMed:9295351) . Plays a key role in cell positioning and movement in lymphoid tissues: 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells (PubMed:22999953) .[UniProtKB/Swiss-Prot Function]
Synonyms
AW261589; D3Ertd552e; hct-1
Gene ID
13123
UniProt
Q60991, Q3USU4
Accession Number mRNA
NM_007825
Chromosomal Location
3 4.98 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
58.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cyp7b1
Species
Mouse
Protein ID
NP_031851
Overview
Purified recombinant protein of Mouse cytochrome P450, family 7, subfamily b, polypeptide 1 (Cyp7b1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/13123
Uniprot URL
https://www.uniprot.org/uniprot/Q60991
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007825
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031851
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