Frs2 (NM_177798) Mouse Recombinant Protein

Product Specifications

Background

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse fibroblast growth factor receptor substrate 2 (Frs2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

4732458E18; C330018A15Rik; Frs2alpha; SNT1

Gene ID

327826

UniProt

Q8C180

Accession Number mRNA

NM_177798

Chromosomal Location

10 D2

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

57.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.