Frs2 (NM_177798) Mouse Recombinant Protein
Product Specifications
Background
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.[UniProtKB/Swiss-Prot Function]
Synonyms
4732458E18; C330018A15Rik; Frs2alpha; SNT1
Gene ID
327826
UniProt
Q8C180
Accession Number mRNA
NM_177798
Chromosomal Location
10 D2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
57.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Frs2
Species
Mouse
Protein ID
NP_808466
Overview
Purified recombinant protein of Mouse fibroblast growth factor receptor substrate 2 (Frs2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/327826
Uniprot URL
https://www.uniprot.org/uniprot/Q8C180
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_177798
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_808466
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