Acvr1 (NM_007394) Mouse Recombinant Protein
Product Specifications
Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved in left-right pattern formation during embryogenesis.[UniProtKB/Swiss-Prot Function]
Synonyms
ActR-I; ActRIA; Acvr; Acvrlk2; Alk-2; ALK2; Alk8; D330013D15Rik; SKR1; Tsk7L
Gene ID
11477
UniProt
P37172
Accession Number mRNA
NM_007394
Chromosomal Location
2 C1.1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
57.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Acvr1
Species
Mouse
Protein ID
NP_031420
Overview
Purified recombinant protein of Mouse activin A receptor, type 1 (Acvr1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11477
Uniprot URL
https://www.uniprot.org/uniprot/P37172
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007394
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031420
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