Zgpat (NM_144894) Mouse Recombinant Protein
Product Specifications
Background
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
1500006I01Rik; BC021513
Gene ID
229007
UniProt
Q8VDM1
Accession Number mRNA
NM_144894
Chromosomal Location
2 H4
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
56.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Zgpat
Species
Mouse
Protein ID
NP_659143
Overview
Purified recombinant protein of Mouse zinc finger, CCCH-type with G patch domain (Zgpat), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/229007
Uniprot URL
https://www.uniprot.org/uniprot/Q8VDM1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_144894
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_659143
Curated Selection
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