Atp6v1b1 (NM_134157) Mouse Recombinant Protein

Non-catalytic subunit of the V1 complex of vacuolar (H+) -ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:16174750, PubMed:23028982) . V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity) . Essential for the proper assembly and activity of V-ATPase (By similarity) . In renal intercalated cells, mediates secretion of protons (H+) into the urine thereby ensuring correct urinary acidification (PubMed:16174750) . Required for optimal olfactory function by mediating the acidification of the nasal olfactory epithelium (PubMed:23028982) .[UniProtKB/Swiss-Prot Function]

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Purified recombinant protein of Mouse ATPase, H+ transporting, lysosomal V1 subunit B1 (Atp6v1b1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug