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Impdh1 (NM_011829) Mouse Recombinant Protein

Product Specifications

Background

Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse inosine monophosphate dehydrogenase 1 (Impdh1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

B930086D20Rik; IMPDH-I

Gene ID

23917

UniProt

P50096

Accession Number mRNA

NM_011829

Chromosomal Location

6 A3.3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

55.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Impdh1

Species

Mouse

Protein ID

NP_035959

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/23917

Uniprot URL

https://www.uniprot.org/uniprot/P50096

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_011829

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_035959

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