Impdh2 (NM_011830) Mouse Recombinant Protein
Product Specifications
Background
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse inosine monophosphate dehydrogenase 2 (Impdh2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
IMPD
Gene ID
23918
UniProt
P24547, Q3UAT9
Accession Number mRNA
NM_011830
Chromosomal Location
9 F2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
55.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Impdh2
Species
Mouse
Protein ID
NP_035960
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/23918
Uniprot URL
https://www.uniprot.org/uniprot/P24547
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_011830
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_035960
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