Stam2 (NM_019667) Mouse Recombinant Protein
Product Specifications
Background
Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex) . The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
1200004O12Rik; 5730456G07Rik; BB145015; Hbp
Gene ID
56324
UniProt
O88811, Q3TGH8
Accession Number mRNA
NM_019667
Chromosomal Location
2 C1.1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
57.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Stam2
Species
Mouse
Protein ID
NP_062641
Overview
Purified recombinant protein of Mouse signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 (Stam2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/56324
Uniprot URL
https://www.uniprot.org/uniprot/O88811
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_019667
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_062641
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