Shoc2 (BC026364) Mouse Recombinant Protein
Product Specifications
Background
Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse soc-2 (suppressor of clear) homolog (C. elegans) (cDNA clone MGC:31051 IMAGE:4014650), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Sur8, Sur-8
Gene ID
56392
UniProt
O88520
Accession Number mRNA
BC026364
Chromosomal Location
19 D2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
58.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Shoc2
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/56392
Uniprot URL
https://www.uniprot.org/uniprot/O88520
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC026364
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