Pus10 (NM_028304) Mouse Recombinant Protein
Product Specifications
Background
Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable) . Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse pseudouridylate synthase 10 (Pus10), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2810013G11Rik; 4933435A13Rik; AU014648; C77560; Ccdc139
Gene ID
74467
UniProt
Q9D3U0
Accession Number mRNA
NM_028304
Chromosomal Location
11
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
59.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Pus10
Species
Mouse
Protein ID
NP_082580
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/74467
Uniprot URL
https://www.uniprot.org/uniprot/Q9D3U0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_028304
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_082580
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