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Npr3 (NM_001039181) Mouse Recombinant Protein

Product Specifications

Background

Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP (PubMed:10377427, PubMed:17951249) . May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects (PubMed:10377427, PubMed:17951249) . May regulate diuresis, blood pressure and skeletal development (PubMed:10377427) . Does not have guanylate cyclase activity (PubMed:10377427) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse natriuretic peptide receptor 3 (Npr3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

ANP-C; ANPR-C; EF-2; lgj; NPR-C; stri

Gene ID

18162

UniProt

Q7TMG7

Accession Number mRNA

NM_001039181

Chromosomal Location

15 5.83 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

59.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Npr3

Species

Mouse

Protein ID

NP_001034270

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/18162

Uniprot URL

https://www.uniprot.org/uniprot/Q7TMG7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001039181

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001034270

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