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Trim26 (NM_001025599) Mouse Recombinant Protein

Product Specifications

Background

E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs) . Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse tripartite motif-containing 26 (Trim26), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AI462198; Zfp173; Zfp1736

Gene ID

22670

UniProt

Q99PN3

Accession Number mRNA

NM_001025599

Chromosomal Location

17 19.16 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

62.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Trim26

Species

Mouse

Protein ID

NP_001020770

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/22670

Uniprot URL

https://www.uniprot.org/uniprot/Q99PN3

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001025599

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001020770

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